Cisplatin cancer research
WebPatients with a tumor response or stabilization continued to receive cisplatin (80 mg/m) and oral vinorelbine (40 mg/m) on days 1 and 8 for two cycles, with concomitant thoracic RT (2 Gy/d, 5 d/wk, and total dose 66 Gy). Results: All patients (n = 38) who received CT-RT were assessable for the tumor response. There were no complete responses. WebOct 5, 2014 · It was discovered to have cytotoxic properties in the 1960s, and by the end of the 1970s it had earned a place as the key ingredient in the systemic treatment of germ …
Cisplatin cancer research
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WebAnnexin XI immunoreactivity inversely correlated with in vitro cisplatin resistance in ovarian cancers (P = 0.01). Decreased expression of Annexin XI is characteristic for cisplatin-resistant cancer cells and may contribute to tumor recurrence. Annexin XI may be a potential marker for chemoresistance and earlier recurrence of ovarian cancer ... WebJul 1, 2024 · Using the platinum-based chemotherapy cisplatin as a model for CICI, we show here that cisplatin suppresses nicotinamide adenine dinucleotide (NAD +) levels …
WebSep 3, 1991 · After a preliminary dose-finding study involving 12 patients with advanced or locally recurrent head and neck cancer, 27 patients were treated on a phase II protocol, using fluorouracil 350 mg/m2/d by continuous intravenous (IV) infusion over 5 days, followed on the sixth day by a 2-hour IV infusion … WebSep 15, 2024 · Cisplatin is the prototype platinum coordination complex classified as an alkylating agent and used intravenously in the treatment of several forms of cancer. Cisplatin has been associated with a low rate of serum enzyme elevations and with rare cases of clinically apparent, acute liver injury.
Web2 days ago · Testicular cancer, also known as testicular germ cell tumors (TGCT), is the most common type of cancer in young men. When treated with cisplatin, the tumor cells stop growing and die. This is... WebApr 11, 2024 · Packiam learned within the last week that his hospital had run low on cisplatin, a chemotherapy drug that is commonly used for bladder cancer and improves the likelihood that surgery will be...
WebCisplatin (DDP) has been a significant tumor chemotherapy against various solid malignant tumors, including lung adenocarcinoma, since it was approved by the Food and Drug Association in 1978.7Platinum chemotherapy drugs, represented by …
WebJournal of Experimental & Clinical Cancer Research is delighted to announce a new thematic series focused on: The role of long non-coding and circular RNAs as potential cancer biomarkers. The 2024 Special Issue will accept Research Articles and Reviews regarding the latest highlights on this topic. Submit here. Submission opens: 1 st January … immortals dungeon masters guide pdfWebApr 13, 2024 · Bonn researchers uncover contribution of protein degradation processes to cisplatin resistance in germ cell tumors: Cisplatin is used successfully in the chemotherapy of testicular cancer. However, patients who develop resistance to the cytostatic drug urgently need alternative therapy options. list of united states flagsWebFor research use only. Cisplatin (NSC 119875, Cisplatinum, cis-diamminedichloroplatinum II, CDDP, cis DDP, DDP) is an inorganic platinum complex, which is able to inhibit DNA … immortals daniel sharmanWebCisplatin (NSC 119875, Cisplatinum, cis-diamminedichloroplatinum II, CDDP, cis DDP, DDP) is an inorganic platinum complex, which is able to inhibit DNA synthesis by conforming DNA adducts in tumor cells. Cisplatin activates ferroptosis and induces autophagy. Solutions are best fresh-prepared. immortals cs:goWebOct 28, 2024 · There have been reports confirming the role of apoptosis as an essential mode of action for several anti-tumour agents, such as alkylating agents including the widely used cisplatin and 1,3- bis (2-chloroethyl)-1-nitrosourea (BCNU) [ 22 ], ionising radiation [ 23 ], topoisomerase inhibitor etoposide, taxol [ 24 ], the tumour necrosis factor (TNF) … immortals disney castWeb2 days ago · Cisplatin is used successfully in the chemotherapy of testicular cancer. However, patients who develop resistance to the cytostatic drug urgently need alternative therapy options. Researchers... list of united states tax casesWebJan 14, 2024 · Cisplatin is one of many chemotherapy drugs. What you will not hear at a cancer center or from your oncologist is how effective is Cisplatin. Introduction When Cisplatin is recommended as a treatment, patients do not know and are not told how effective the drug is against cancer. list of universal studios orlando