Ligustrazine aromatic acid ether derivatives
Nettet27. okt. 2008 · Ligustrazine aromatic acid ether derivative, its preparation method, pharmaceutical composition, and application 1 Europe PMC requires Javascript to … NettetProcedures used for synthesis of ligustrazine ether derivatives are shown in Scheme 2. Combining different carbon chains and ligustrazine resulted in synthesis of three ... aromatic acid derivatives were also synthesized (Compounds 50–55)[19]. Wang …
Ligustrazine aromatic acid ether derivatives
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Nettet30. sep. 2013 · reacted with 3,5,6-trim eth ylp yraz ine-2-ca rbo xyli c aci d (2) catalyzed by 1- ... ligustrazine-aromatic acid derivatives and thei r inhibitory effect on platelet aggregation. Chin. J. Nettetfrom publication: Synthesis and Protective Effect of New Ligustrazine-Benzoic Acid Derivatives against CoCl2-Induced Neurotoxicity in Differentiated PC12 Cells A …
Nettet[origin: EP2213666A1] Ligustrazine aromatic acid ether derivative of general formula I, its preparation method, pharmaceutical composition and application, wherein Ar is … NettetLigustrazine aromatic acid ether derivative of general formula I, its preparation method, pharmaceutical composition and application, wherein Ar is selected from aryl substituted aryl and substituted styryl, R is selected from hydrogen and alkyl with no more than 6 …
Nettet11. apr. 2024 · Antiplatelet aggregation agents have demonstrated clinical benefits in the treatment of ischemic stroke. In our study, a series of novel nitric oxide (NO)-donating ligustrazine derivatives were designed and synthesized as antiplatelet aggregation agents. They were evaluated for the inhibitory effect on 5′-diphosphate (ADP)-induced … Nettet27. okt. 2008 · ligustrazine aromatic acid ether derivative, its preparation method, pharmaceutical composition, and application 1 Europe PMC requires Javascript to …
NettetEP2213666A1 EP08843800A EP08843800A EP2213666A1 EP 2213666 A1 EP2213666 A1 EP 2213666A1 EP 08843800 A EP08843800 A EP 08843800A EP 08843800 A …
Nettet10. mar. 2024 · Ligustrazine-benzoic acid derivatives. Many aromatic acids, such as protocatechuic acid, vanillic acid and salicylic acid showed interesting neuroprotective … as tempelman salarisNettetMicellar conditions are a new direction of study for ether synthesis as they are simple, efficient, economical and environmentally friendly. 1. Introduction Ethers are a class of organic compounds characterized by an oxygen atom bonded to two alkyl or aryl groups (e.g. R–O–R0). Generally ethers may be categorized as aryl ether, allyl ether, as teman handpanNettet13. feb. 2024 · A mixed or unsymmetrical anhydride is a carboxylic acid anhydride that has the following general structural formula. where R 1 ≠R 2, but are hydrogen atoms, alkyl groups, aryl groups. When naming unsymmetrical acid anhydrides, name both using alkanoic general method and then put the two names alphabetically. as tempelmannNettet9. feb. 2024 · A series of ligustrazine-phenolic acid esters which exhibited promising neuroprotective activities have previously been reported. Nevertheless, we found that … as tembak ufoNettetLigustrazine aromatic acid ether derivative of general formula I, its preparation method, pharmaceutical composition and application, wherein Ar is selected from aryl substituted aryl and substituted styryl, R is selected from hydrogen and alkyl with no more than 6 carbon atoms. Log In Sign Up. as tembagaNettetA series of novel ligustrazine-benzoic acid derivatives were synthesized and evaluated for their protective effect against cobalt chloride-induced neurotoxicity in differentiated PC12 cells. Combining hematoxylin and eosin staining, we found compound that (3,5,6-trimethylpyrazin-2-yl)methyl 3-methoxy-4-[(3,5,6-trimethylpyrazin-2 … asun membersNettetAccording to different conjunctive positions and numbers of hydroxyls, over 100 novel ligustrazine-phenolic acid derivatives were synthesized and were proved to possess … asun men's baseball standings