WebMar 24, 2024 · Conventional drug screening methods search for a limited number of small molecules that directly interact with the target protein. This process can be slow, cumbersome and has driven the need for developing new drug screening approaches to counter rapidly emerging diseases such as COVID-19. We propose a pipeline for drug … WebJohn Erol Evangelista (Mt Sinai) introduced the SigCom LINCS API which contains over 1.5 million gene expression signatures from LINCS, the Gene Expression Tissue Project (GTEx), and Gene Expression Omnibus databases (GEO). Then, Daniel Clarke (Mt Sinai) gave an introduction to building Appyters and how to use the SigCom LINCS APIs within Appyters.
Data Portal for the Library of Integrated Network-based Cellular ...
WebSep 3, 2024 · Methods: We collected 10 public HCC gene signatures and evaluated them by utilizing four different (commercial and non-commercial) gene expression profile comparison tools: Oncomine Premium, SigCom LINCS, ProfileChaser (modified version), and GENEVA, which can assign similar pre-analyzed profiles of patients with tumors or cancer … WebI queried some up and down-regulated genes on sigcom web, there were some results from different data source, and here are two of them: Could you tell what's the difference between "LINCS L1000 Chemical Perturbations (2024)" and "LINCS L1000 Chemical Perturbations Consensus Signatures" highlighted by the red rectangle? how do fish absorb mercury
SigCom LINCS: data and metadata search engine for a million …
WebAPI - LINCS chemical perturbagen signatures · Issue #70 · MaayanLab/sigcom-lincs · GitHub. MaayanLab / sigcom-lincs Public. Notifications. Fork 2. Star 1. Issues. Actions. … WebSigCom LINCS is a webserver that serves over a million gene expression signatures processed, analyzed, and visualized from LINCS, GTEx, and GEO. SigCom LINCS is built with Signature Commons, a ... WebSigCom LINCS is a webserver that serves over a million gene expression signatures processed, analyzed, and visualized from LINCS, GTEx, and GEO. SigCom LINCS is built with Signature Commons, a cloud-agnostic skeleton Data Commons with a focus on serving searchable signatures. SigCom LINCS provides a rapid signature similarity search for ... how do fish absorb oxygen